Last edited by Goltir
Monday, May 4, 2020 | History

4 edition of Coagulation disorders in the cancer patient found in the catalog.

Coagulation disorders in the cancer patient

by Eric J. Seifter

  • 362 Want to read
  • 10 Currently reading

Published by Futura Pub. Co. in Mount Kisco, N.Y .
Written in English

    Subjects:
  • Cancer -- Complications.,
  • Blood coagulation disorders.

  • Edition Notes

    Statementby Eric J. Seifter, William R. Bell.
    ContributionsBell, William Robert, 1937-
    Classifications
    LC ClassificationsRC262 .S446 1984
    The Physical Object
    Paginationxii, 212 p. :
    Number of Pages212
    ID Numbers
    Open LibraryOL2876292M
    ISBN 100879932279
    LC Control Number84080630

    Coagulation Disorders: Definition Coagulation disorders deal with disruption of the body's ability to control blood clotting. The most commonly known coagulation disorder is hemophilia, a condition in which patients bleed for long periods of time before clotting. There are other coagulation disorders with a variety of causes. Description. Find information about and book an appointment with Dr. Richa Dawar, MD in Hollywood, FL, Miami, FL. Specialties: Anemia and Bone Marrow Disorders, Breast Medical Oncology, Hematologic Coagulation Disorders, Medical Oncology, Thoracic Medical Oncology/5(97).

    Book Your Hotel Exhibitor Information Expert Medical Societies Release Multidisciplinary Recommendations for Breast Cancer Patient Care During COVID Pandemic; Giannis D, Ziogas IA, Gianni P. Coagulation disorders in coronavirus infected patients: COVID, SARS-CoV-1, MERS-CoV and lessons from the past.   The risk of developing VTE increases in the presence of cancer, chemotherapy, and surgery. 2 Malignancy and chemotherapy augment the risk of VTE by greater than fourfold and fold, respectively, for an estimated yearly incidence of 1 per patients with cancer. 3 Cancer cells interact with monocytes and macrophages releasing tumor necrosis.

    Severe liver disease (eg, cirrhosis, fulminant hepatitis, acute fatty liver of pregnancy) may disturb hemostasis by impairing clotting factor e all coagulation factors are made in the liver (by hepatocytes and endothelial cells), both the prothrombin time (PT) and partial thromboplastin time (PTT) are prolonged in severe liver disorders. At a Glance Disseminated intravascular coagulation (DIC) is a potentially life-threatening disorder that involves a pathological activation of coagulation system. This clinical syndrome can be Author: Majed Refaai.


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Coagulation disorders in the cancer patient by Eric J. Seifter Download PDF EPUB FB2

Cancer patients frequently develop alterations in hemostasis including platelet abnormalities, abnormal activation of the coagulation cascade, release of plasminogen activator, and decreased hepatic synthesis of anticoagulant and coagulant proteins (see Table ). 62 Platelet aggregation and activation in cancer patients may be triggered by the shedding of membrane glycolipids into the host circulation by.

Additional Physical Format: Online version: Seifter, Eric J. Coagulation disorders in the cancer patient. Mount Kisco, N.Y.: Futura Pub. Co.,   A short monograph on the hemostatic process; disorders of platelets, coagulation factors, and vessels; disseminated intravascular coagulation; thrombosis; and metastases.

The interpretive text is almost outweighed by illustrative cases; citation of references by the author name-and-date system slows the reader. • Vascular bleeding due to cancer invasion or therapy-related complications is very common.

• Medical causes of clinically relevant bleeding in cancer include the use of antithrombotics, thrombocytopenia, qualitative defect in platelets, coagulation defects.

About this book Coagulation in Cancer informs medical professionals working in the field of cancer of the pathophysiologic mechanisms of cancer-related thrombosis and bleeding. It provides assistance in recognizing the various bleeding and clotting disorders associated with cancer and includes current recommendations for the management of hemorrhage, and prevention and treatment of thrombosis in the patient with malignancy.

This volume is a valuable addition to the literature on cancer and coagulation. DIC is the most frequent coagulation disorder associated with prostate cancer.

The chronic form of DIC is characterized by increased bleeding tendency and excessive prothrombin time by: Bleeding disorders, a type of coagulation disorders, occur when our bodies cannot clot blood effectively, so excessive amounts of blood can leave the vessels, and there is less blood available in our body’s circulation to carry nutrients, exchange carbon dioxide and oxygen with our tissues, and remove waste products of metabolism.

In a group of unselected patients with disseminated malignancies, marked disturbances in the coagulation and fibrinolytic systems were found. Mean silicone coagulation time was shortened, and fibrinogen levels were markedly by:   In the s, the French physician Armand Trousseau reported the occurrence of ‘mysterious’ thrombotic disorders in cancer patients and concluded that spontaneous blood coagulation events are frequent in these individuals because of a ‘special crisis in their blood’.

Later, his name was used to designate the manifestation of thrombophlebitis in patients with malignant neoplasias-Trousseau's by: "This comprehensive book, Coagulation in Cancer, edited by David Green and Hau C.

Kwaan is a much needed compilation of recent studies and current concepts of the subject. Many will appreciate the chapters emphasizing the high probability of thromboembolism and bleeding and myeloproliferative disorders Format: Hardcover.

Coagulation disorders are disruptions in the body’s ability to control blood clotting. Coagulation disorders can result in either a hemorrhage (too little clotting that causes an increased risk of bleeding) or thrombosis (too much clotting that causes blood clots to obstruct blood flow).These clotting disorders develop due to several conditions.

Excerpt A short monograph on the hemostatic process; disorders of platelets, coagulation factors, and vessels; disseminated intravascular coagulation; thrombosis; and metastases. The interpretive t.

Coagulopathy leading to ICH in cancer patients may be associated with disseminated intravascular coagulation (DIC), thrombocytopenia due to bone marrow suppression or infiltration by tumor, liver failure, or vitamin K deficiency.

In this hematology sequence, students learn to recognize and diagnose anemias, bleeding and clotting disorders, and abnormal white blood cell and lymphocyte disorders. Students learn the clinical approach to a patient with a red blood cell, hemostatic or thrombotic, and white blood cell disorder.

Disseminated intravascular coagulation is an intermediary mechanism of disease and is always due to an underlying disorder such as malignancy. When dealing with patients with cancer‐related DIC, it is useful to consider the different pathogenetic mechanisms that Cited by: "This comprehensive book, Coagulation in Cancer, edited by David Green and Hau C.

Kwaan is a much needed compilation of recent studies and current concepts of the subject. Many will appreciate the chapters emphasizing the high probability of thromboembolism and bleeding and myeloproliferative disorders Manufacturer: Springer. In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject.

Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer.

The patient was admitted with a deep vein thrombosis. Doppler examination was positive for thrombosis right tibial vein. The patient was treated for DVT a couple of years ago. Because of recurrent thrombosis, the patient was assessed for coagulation disorders and was found to have protein S deficiency.

Coagulation disorders are common in cancer patients and, unknown to many, thrombosis (a blood clot and type of coagulation disorder) is the second most frequent cause of death in cancer patients [1].

Additionally, more than 40% of patients who receive chemotherapy have coagulation disorders. Coagulation disorders are common in leukemia patients.

The incidence of thromboembolism (TE) in hematologic malignancies (including lymphoma and. Coagulation and cancer. Analysis of the role of thrombomodulin in all-trans retinoic acid treatment of coagulation disorders in cancer patients Hamed Ghaffari, Jeffrey D Cited by: People with cancer are at an increased risk of developing these dangerous blood clots.

Research has shown that there is a clear connection between cancer and DVT. This is because some of the genetic changes that cause cancer increase the activation of clotting factors.